2022

Multimodal analysis of the differential effects of cyclic strain on collagen isoform composition, fibril architecture and biomechanics of tissue engineered tendon, Journal of Tissue Engineering, 2022, 13, 20417314221130486.

S'Dravious, A.D.; Ogle, M.E.; Vyshnya, S.; Chiappa, N.F.; Leitmann, B.; Rudy, R.; Day, A.; Mortensen, L.J.; Kurtzberg, J.; Roy, K.; Botchwey, E.A. Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids, Cytotherapy, 2022, 24, 608.

2021

Daga, K.R.; Priyadarshani, P.; Larey, A.M.; Rui, K.; Mortensen, L.J.; Marklein, R.A. Shape up before you ship out: morphology as a potential critical quality attribute for cellular therapies, Current Opinion in Biomedical Engineering, 2021, 20, 100352.

Cifuentes, S.J.; Priyadarshani, P.; Castilla‐Casadiego, D.A.; Mortensen, L.J.; Almodóvar, J.; Domenech, M. Heparin/collagen surface coatings modulate the growth, secretome, and morphology of human mesenchymal stromal cell response to interferon‐gamma, Journal of Biomedical Materials Research Part A, 2021, 109, 951.

San Emeterio, C.L.; Hymel, L.A.; Turner, T.C.; Ogle, M.E.; Pendleton, E.G.; York, W.Y.; Olingy, C.E.; Liu, A.Y.; Lim, H.S.; Sulchek, T.; Mortensen, L.J.; Qiu, P.; Jang, Y.C.; Willett, N.J.; Botchwey, E.A. Sustained Delivery of Bioactive Lipids Enhances Muscle Fiber Regrowth and Orientation Following Volumetric Muscle Loss, Frontiers Bioengineering and Biotechnology, 2021, 9, 650289.

Figueroa, J.; Blum, J.E.; Tehrani, K.F.; Yin, H.; Mortensen, L.J.; Thalacker-Mercer, A.E.; Greising, A.M.; Call, J.A. Lifelong Ulk1-mediated autophagy deficiency in muscle induces mitochondrial dysfunction and contractile weakness, International Journal of Molecular Sciences, 2021, 22, 1937.

Tehrani, K.F.; Pendleton, E.G.; Southern, W.M.; Call, J.A.; Mortensen, L.J. Spatial frequency metrics for analysis of musculoskeletal tissues using multi-photon microscopy, Connective Tissue Research, 2021, 62, 4-14.

Tehrani, K.F.; Koukourakis, N.; Czarske, J.; Mortensen, L.J. In situ measurement of the isoplanatic patch for imaging through intact bone, J. Biophotonics, 2021, 14, e202000160.

2020

Tehrani, K.F.; Koukourakis, N.; Czarske, J.; Mortensen, L.J. In situ measurement of the isoplanatic patch for imaging through intact bone, J. Biophotonics, 2020, e202000160.

Cifuentes, S.J.; Priyadarshani, P.; Castilla-Casadiego, D.A.; Mortensen, L.J.; Almodóvar, J.; Domenech, M. Heparin/Collagen Surface Coatings Improve Viability and Immunomodulatory Signals of Human Mesenchymal Stromal Cell Response to Interferon Gamma, Journal of Biomedical Materials Research: Part A, 2020, early online.

Pendleton, E.G. §; Tehrani, K.F.; Barrow, R.; Mortensen, L.J. Second Harmonic Generation Polarimetry of Collagen Organization in Whole Bone, Biomed. Opt. Express, 2020, 11, 4379-4396.

2019

Nichenko, A.S.; Southern, W.M.; Tehrani, K.F.; Qualls, A.E.; Flemington, A.B.; Mercer, G.H.; Yin, A.; Mortensen, L.J.; Yin, H.; Call, J.A. Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice, J. Physiol. Cell Physiol., 2019, 318, C242-C252.

Tehrani, K.F.; Latchoumane, C.F.; Southern, W.M.; Pendleton, E.G.; Maslesa, A.; Karumbaiah, L.; Call, J.A.; Mortensen, L.J. 5D two-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing, Biomedical Optics Express, 2019, 10, 3591-3604.

Southern, W.M.; Nichenko, A.S.; Tehrani, K.F.; McGranahan, M.J.; Krishnan, L.; Qualls, A.E.; Jenkins, N.T.; Mortensen, L.J.; Yin, H.; Yin, A.; Guldberg, R.E.; Greising, S.M.; Call, J.A. PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury, Scientific Reports, 2019, 9, 1-17. 

Yoshida, Y.; Wang, Z.; Tehrani, K.F.; Pendleton, E.G.; Tanaka, R.; Mortensen, L.J.; Nishimura, S.; Tabata, S.; Liu, H.; Kawabata, F. Bitter taste receptor T2R7 and umami taste receptor subunit T1R1 are expressed highly in Vimentin-negative taste bud cells in chickens, BBRC, 2019, 511, 280-286.

2018

Latchoumane, C.F.; Jackson, L.; Sendi, M.S.E.; Tehrani, K.F.; Mortensen, L.J.; Stice, S.L.; Ghovanloo, M.; Karumbaiah, L. Chronic Electrical Stimulation Promotes the Excitability and Plasticity of ESC-derived Neurons following Glutamate-induced Inhibition In vitro, Scientific Reports, 2018, 8, 1-16.

Selma, J.M.; Anusuya Das, A.; Awojoodu, A.O.; Wang, T.; Kaushik, A.P.; Cui, Q.; Song, H.; Ogle, M.E.; Segar, C.E.; Pendleton, E.G.; Tehrani, K.F.; Mortensen, L.J.; Botchwey, E.A. Novel Lipid Signaling Mediators for Mesenchymal Stem Cell Mobilization During Bone Repair. Cellular and Molecular Bioengineering, 2018, 11, 241-253.

Shao, L.; Chang, J.; Feng, W.; Wang, X.; Williamson, E.A.; Li, Y.; Schajnovitz, A.; Scadden, D.; Mortensen, L.J.; Lin, C.P.; Li, L.; Downing, J.; Zhou, D.; Hromas, R.A. The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow, Nature Communications, 2018, 9, 2377.

Tehrani, K.F.; Pendleton, E.G.; Southern, W.M.; Call, J.A.; Mortensen, L.J. Two-photon deep-tissue spatially resolved mitochondrial imaging using membrane potential fluorescence fluctuations, Biomedical Optics Express, 2018, 9, 254-259.

2017

Turcotte, R.; Alt, C.; Runnels, J.; Ito, K.; Wu, J.W.; Zaher, W.; Mortensen, L.J.; Silberstein, L.; Cote, D.C.; Kung, A.L.; Ito, K.; Lin, C.P. Image-guided transplantation of single cells in the bone marrow of live animals. Scientific Reports, 2017, 7, 3875.

Wilk, K.*; Yeh, S.-C.A.*; Mortensen, L.J.*; Ghaffarigarakani, S.; Lombardo, C.M.; Bassir, S.H.; Lin, C.P.; Intini, G. Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration. Stem Cell Reports, 2017, 8, 933-946.

Tehrani, K.F.; Kner, P.; Mortensen, L.J. Characterization of wavefront errors in mouse cranial bone using second-harmonic generation. Journal of Biomedical Optics, 2017, 22, 036012.

Zheng, H.; Mortensen, L.J.; Ravichandran, S.; Bentley, K.; DeLouise, L.A. Effect of Nanoparticle Surface Coating on Cell Toxicity and Mitochondria Uptake. Journal of Biomedical Nanotechnology, 2017, 13, 155-166.

2016

Goodfellow, F.; Simchick, G.A.; Mortensen, L.J.; Stice, S.L.; Zhao, Q. Tracking and Quantification of Magnetically Labeled Stem Cells using Magnetic Resonance Imaging. Advanced Functional Materials, 2016, 26, 3899-3915.

Rajapaksha, P.; Venkatesan, N.; Wang, Z.; Tehrani, K.F.; Payne, J.; Swetenburg, R.L.; Kawabata, F.; Tabata, S.; Mortensen, L.J.; Stice, S.L.; Beckstead, R.; Liu, H. Labeling and analysis of chicken taste buds using molecular markers in oral epithelial sheets. Scientific Reports, 2016, 6, 37247.

Yang, Z.; Concannon, J.; Seyb, K.; Mortensen, L.J.; Ng, K.S.; Ranganath, S.; Gu, F.; Levy, O.; Zhao, W.; Lin, C.P.; Glicksman, M.A.; Karp, J.M. Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation. Scientific Reports, 2016, 6, 30263.

Dykstra, B.*; Lee, J.*; Mortensen, L.J.*; Yu, H.; Wu, Z.L.; Lin, C.P.; Rossi, D.J.; Sackstein, R. Glycoengineering of E-Selectin Ligands by Intracellular versus Extracellular Fucosylation Differentially Affects Osteotropism of Human Mesenchymal Stem Cells. Stem Cells, 2016, 34, 2501-2511.

2015

Mortensen, L.J.; Hill W.D. (2015) Skeletal stem cells for bone development, homeostasis and repair: one or many?. BoneKEy Reports, 2015, 4.

Publications prior to UGA

2015

Mortensen, L.J.; Faulknor, R.; Ravichandran, S.; Zheng, H.; DeLouise, L.A. UVB Dependence of Quantum Dot Reactive Oxygen Species Generation in Common Skin Cell Models. Journal of Biomedical Nanotechnology, 2015, 11, 1644-1652.

Leuchner, F.; Courties, G.; Dutta, P.; Mortensen, L.J.; Gorbatov, R.; Sena, B.; Novobrantseva, T.I.; Borodovsky, A.; Fitzgerald, K.; Iwamoto, Y.; Lasitshcka, F.; Meder, B.; Katus, H.A.; Lin, C.P.; Libby, P.; Anderson, D.G.; Swirksi, F.K.; Weissleder, R.; Nahrendorf, M. Silencing of CCR2 in myocarditis. European Heart Journal, 2015, 36, 1478–1488.

Levy*, O.; Mortensen*, L.J.; Boquet*, G.; Perrault, C.; Benhamou, B.; Zhang, J.; Stratton, T.; Han, E.; Safaee, H.; Yang, Z.; Moulton, M.-C.; Rothblatt, J.; Deleuze, J.-F.; Lin, C.P.; Karp, J.M. A small-molecule screen for enhanced homing of systemically infused cells. Cell Reports, 2015, 10, 1261-1268.

Mortensen, L.J.; Alt, C.; Turcotte, R.; Masek, M.; Liu, T.; Xu, C.; Intini, G.; Lin, C.P. Femtosecond laser bone ablation with a high repetition rate fiber laser source. Biomedical Optics Express, 2015, 6, 32-42.

2014

Lee, S.K.; Mortensen, L.J.; Lin, C.P.; Tung, C.-H. An authentic cell fate tracker: from beginning to end, Nature Communications, 2014, 5, 5216.

Turcotte, R.; Alt, C.; Mortensen, L.J.; Lin, C.P. Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy, Biomedical Optics Express 2014, 5, 3578.

Alt, C.; Runnels, J.M.; Mortensen, L.J.; Zaher, W.; Lin, C.P. In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment, Invest. Ophthalmol. Vis. Sci. 2014, 55, 5314.

Ksander, B.R.; Kolovou, P.E.; Saab, K.R.; Wilson, B.J.; Guo, Q.; Ma, J.; Gregory, M.S.; Perez, V.L.; Mortensen, L.J.; Alt, C.; Cruz-Guilloty, F.; Vincent, W.J.B.; McGuire, S.P.; Kao, W.W.Y.; Call, M.K.; Lin, C.P.; Tucker, B.A.; Frank, M.H.; Frank, N.Y. A limbal stem cell gene required for corneal development and repair, Nature 2014, 511, 353. 

Spencer, J.A.; Ferraro, F.; Roussakis, E.; Klein, A.; Wu, J.; Mortensen, L.J.; Alt, C.; Runnels, J.M.; Vinogradov, S.A.; Scadden, D.T.; Lin, C.P. Direct measurement of local oxygen concentration in the bone marrow of live animals, Nature 2014, 508, 269.

2013

Mortensen, L.J.; Levy, O.; Phillips, J.A.; Stratton, T.; Triana, B.; Ruiz, J.P.; Gu, F.; Karp, J.M.; Lin, C.P. Quantification of Mesenchymal Stem Cell (MSC) delivery to a target site using in vivo confocal microscopy, PLOS ONE 2013, 8, e78145.

Levy, O.; Zhao, W.; Mortensen, L.J.; LeBlanc, S.; Tsang, K.; Fu, M.; Phillips, J.A.; Sagar, V.; Anandakumaran, P.; Ngai, J.; Eimon, P.; Angel, M.; Lin, C.P.; Yanik, M.F.; Karp, J.M. mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation, Blood 2013, 122, e23.

Pestana, N.; Mortensen, L.J.; Runnels, J.; Vickers, D. Murthy, S.K.; Lin, C.P.; Niedre, M. An Improved Prototype Diffuse Fluorescence Flow Cytometer for High Sensitivity Detection of Rare Circulating Cells In Vivo, J. Biomed. Optics 2013, 18, 77002.

Zheng, H.; Mortensen, L.J.; DeLouise, L.A. Thiol Antioxidant-Functionalized CdSe/ZnS Quantum Dots: Synthesis, Characterization, Cytotoxicity, J. Biomed. Nanotech. 2013, 9, 382.

Mortensen, L.J.; Jatana, S.; Gelein, R.; De Benedetto, A.; De Mesy Bentley, K.L.; Beck, L.A.; Elder, A.; DeLouise, L.A. Quantification of quantum dot murine skin penetration with UVR barrier impairment, Nanotoxicology 2013, 7, 1386.

Mortensen, L.J.; Ravichandran, S.; DeLouise, L.A. The impact of UVB exposure and differentiation state of primary keratinocytes on their interaction with quantum dots, Nanotoxicology, 2013, 7, 1244. 

2008-2012

Sarkar, D.; Spencer, J.A.; Phillips, J.A.; Zhao, W.; Schafer, S.; Spelke, D.P.; Mortensen, L.J.; Ruiz, J.P.; Vemula, P.K.; Sridharan, R.; Kumar, S.; Karnik, R.; Lin, C.P.; Karp, J.M. Engineered Cell Homing, Blood 2011, 118, e184.

Mortensen, L.J.; Glazowski, C.E.; Zavislan, J.M.; DeLouise, L.A. Near-IR confocal microscopy for imaging of quantum dots in mammalian skin, Biomedical Optics Express 2011, 2, 1610.

Ravichandran, S.; Mortensen, L.J.; DeLouise, L.A. Quantification of human skin barrier function and susceptibility to quantum dot skin penetration, Nanotoxicology 2011, 5, 675.

Mortensen, L.J.; Ravichandran, S.; Zheng, H.; DeLouise, L.A. Progress and challenges in quantifying skin permeability to nanoparticles using a quantum dot model, J. Biomed. Nanotech. 2010, 6, 596.

Mortensen, L.J.; Oberdorster, G.; Pentland, A.P.; DeLouise, L.A. In Vivo Skin Penetration of Quantum Dot Nanoparticles in the Murine Model: The Effect of UVR, Nano Lett. 2008, 8, 2779.