Intravital imaging of cell & organelle dynamics
Multi photon evaluation of cellular and organelle dynamics in living mammals
Rapid volumetric imaging for bone marrow blood flow
Blood cell quantification
Mitochondrial depolarization kinetics
Mitochondrial depolarization frequency neighborhoods
Tissue aberration quantification & scattering correction
Measurement & modeling of bone tissue scattering aberrations towards deeper imaging
Point spread function into the bone
Quantification of point spread function with depth
Iterative phase correction to enhance point spread function in scattering media
Mesenchymal stromal cell (MSC) biomanufacturing
& engineering
Imaging-centric investigation & enhancement of stem cell therapeutic potency
MSC culture dynamics
MSC shape discrimination
In vivo competitive MSC homing
Imaging characterization of 3D differentiating microsphere cultures
Quantification of tissue health and regeneration
Multiphoton imaging evaluation of tissue health, injury and regeneration in wound repair and metabolic bone disorders
Polarimetric second harmonic generation identifies collagen order defect in bone disease hypophosphatasia
Image texture quantification of polarimetric second harmonic generation identifies impaired collagen order in hypophosphatasia
Bone defect infiltration (A) & bone regeneration (B) by cells derived from Prx1-skeletal progenitors
Quantification of muscle mitochondria organization after volumetric muscle loss