https://mortensenlab.com/home daily 1.0 2021-04-21 https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618255589589-O6HQILPERV59FL2ENFNZ/Mortensen%252Blab%252Bgroup%252Bshot.jpg Home - We are a highly interdisciplinary team. Our lab team brings together years of experience in biomedical biology, electrical engineering, optics and regenerative medicine. https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618853164602-GZPTY2QCR6M82OKWNL0V/MAX_Line137_Day4_OsteoMax_5k_00010_LUT+TEST.png Home - Our research We seek to understand the function & dynamics of living cells in musculoskeletal organs using multi photon optical microscopy. We are developing new tools to investigate sub cellular dynamics deep in highly scattering tissue— providing insight into cell and tissue health and regeneration. Of particular interest is understanding and controlling the fate of biomanufactured therapeutic cells. https://mortensenlab.com/gallery-2 daily 0.75 2021-04-19 https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618422741758-57B4FYCKQ58B3ZRJBCNU/image1.png Research - Intravital imaging of cell & organelle dynamics Multi photon evaluation of cellular and organelle dynamics in living mammals https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618428307182-82LH610A7GL36D2P6SKJ/JBO_22_3_036012_f002.png Research - Tissue aberration quantification & scattering correction Measurement & modeling of bone tissue scattering aberrations towards deeper imaging https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618597364221-CI0B3368119Y8LEGZCY5/HighPotencyDonor_ColorCodedPotency.png Research - Mesenchymal stromal cell (MSC) biomanufacturing & engineering Imaging-centric investigation & enhancement of stem cell therapeutic potency https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618756372702-36PZUPJXG9CHMTQSQIJQ/bone+polarimetry+image.001.jpeg Research - Quantification of tissue health and regeneration Multiphoton imaging evaluation of tissue health, injury and regeneration in wound repair and metabolic bone disorders https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/450206e4-0f9c-43d1-ba82-cb52c0d32257/bone+marrow+video+shorter.gif Research Rapid volumetric imaging for bone marrow blood flow https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/5b4ee16c-42b8-4e24-a9ca-6952cf08927a/bone+psf+depth.gif Research Point spread function into the bone https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1c8b2ee9-0cdc-44c1-b099-c6a1ca79b019/image40color512.gif Research MSC culture dynamics https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/6c4a4515-f419-46e2-b2d3-2616b3347357/WT_HPP+bone.001.jpeg Research Polarimetric second harmonic generation identifies collagen order defect in bone disease hypophosphatasia https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/818dd51e-2266-4f99-94d7-a5147498cf62/psf+with+depth.png Research Quantification of point spread function with depth https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/5be19ef2-bdf4-4dfc-b839-9483c004a40f/imaging+pca.001.jpeg Research MSC shape discrimination https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/917cb5b8-b571-463f-973f-79b97bbde2db/bone+texture.001.jpeg Research Image texture quantification of polarimetric second harmonic generation identifies impaired collagen order in hypophosphatasia https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1d3a6f23-2ca3-48a1-8bc6-2fc01f09834b/ezgif-7-2b7a4cf23b3c.gif Research In vivo competitive MSC homing https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/3f67e42a-1e30-4483-bd6d-af9aeffb97ce/bone+regeneration.001.jpeg Research Bone defect infiltration (A) & bone regeneration (B) by cells derived from Prx1-skeletal progenitors https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/324bac49-1600-40ff-9086-5c452140cb5d/getImage.xqy.jpeg Research Blood cell quantification https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/5557a2de-356a-445b-bb74-25601954320a/3D+cell+characterization.001.jpeg Research Imaging characterization of 3D differentiating microsphere cultures https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/40a33694-b5be-4f20-bed8-9269e8814f51/Substack+%281-550%29.gif Research Iterative phase correction to enhance point spread function in scattering media https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/772587dd-7666-470d-bdfb-869503863505/ezgif-7-78a781004452.gif Research Mitochondrial depolarization kinetics https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/e0c258c0-26ca-4e1a-86f8-a1a401b4c250/living+muscle+mitochondrial+flickering+frequency.001.jpeg Research Mitochondrial depolarization frequency neighborhoods https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618841548516-MS1H3T7R12US1BNYJQS2/vml%2Bimaging.001.jpg Research Quantification of muscle mitochondria organization after volumetric muscle loss https://mortensenlab.com/contact-us daily 0.75 2021-04-19 https://mortensenlab.com/publications daily 0.75 2024-02-08 https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618843690714-KIND87WSSGDY6O0QRESX/jbio_v14-i1_IC2_jbio.202170003.png Publications https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618843857125-X19I26L9RIVVR09UGE3J/AJP+Cell+Cover_Jan+-+Mar+2020.png Publications https://mortensenlab.com/the-team daily 0.75 2024-02-08 https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618254404684-NGQY0EPSD5U8SW8X9B5D/Mortensen%252C%2BLuke_2.jpg The Team - Luke Mortensen Associate Professor Regenerative Medicine & Biomedical Engineering https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1623348774516-GMQVRI3GWWPVLC068MYA/image13.jpg The Team - Joseph (Junior) Ametepe MS student Biomedical Engineering https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618257275885-0IKBSYTZEIUVXFQFKWAW/Head%252BShots-30.jpg The Team - Adrian Liversage PhD student Biomedical Engineering https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618254856658-C6682JM70HSWPQ3BI41C/Head%2BShots-27.jpg The Team - Priyanka Priyadarshani Tobias Keene, D.D.S. Hailing from Richmond, Virginia, Dr. Tobias Keene brings a bit of unabashed Southern hospitality to all his patients. He moved to Washington, D.C. over thirty years ago as a freshman at Ivy College. Right after graduation, he attended World University’s School of Dentistry. Before opening Keene Dental in 1994, he worked for free clinics and some of the finest practices in the District. He is part of the 123 Dental Association and stays up-to-date on the latest dental discoveries. When not striving to keep his patients happy and healthy, he’s enjoys hiking with his family in Rock Creek Park. https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618373866703-CT6GN5OTDKZ3YQJCN1AG/IMG_0780.jpg The Team - Kejie (Jessica) Rui PhD student Biomedical Engineering https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618414591128-QIW2ODXHVBT8ELIBVRO6/IMG_0130.jpg The Team - Tianyi Zheng PhD student Electrical Engineering https://images.squarespace-cdn.com/content/v1/606b2d263871c45648c6dc07/1618939798281-QLFPJ6EPNSCNAOFSGLUK/FB5A3D90-5A4F-46D5-A6C1-35D4B901F491_1_201_a.jpg The Team - Sarah Franklin MS student Biomedical Engineering